Itch

Over many years of my professional life, I studied the interminable whole body itchiness that many patients with certain kinds of liver disease suffer from. Although I made progress in understanding this common and debilitating symptom, and found a partially effective new treatment, the ultimate cause is still a mystery that I am still curious about. As far as I know no one has come up with what evolutionary benefit could be concurred on someone forced to scratch themselves raw, but I suspect it is somehow linked to the disturbed Vitamin D metabolism in liver diseases, allowing more production of it from sunlight in deeper skin layers